Tramadol Vs Hydrocodone

What are the Differences Between Tramadol and Hydrocodone?

What Is Tramadol?

Tramadol, as some of you may know, is a part of the opiate family. This medication is typically prescribed as an analgesic; which is a type of drug known for relieving pain.

Tramadol is considered to be an analgesic due to its properties of being less addictive and having a better safety profile when compared to other opiates in the family. However, like any other medication, it has its negative aspects.

The potentially dangerous side effects that occur with this particular drug are seizures and serotonin syndrome.

In light of the fact that these symptoms exist, they do not happen unless you are partaking in Tramadol monotherapy, misusing this medication, or are taking other medications such as antidepressants. (1)

What are the Side Effects of Tramadol?

A few of the most common side effects that this medication has are as follows in the list below.

• Feeling agitated
• Diarrhea
• Feeling warm
• Feeling cold
• Heartburn
• Joint pain
• Restlessness
• Lack of concentration

This medication has other more severe side effects, but they are incredibly less common and rare.

A Peek into Serotonin Syndrome

For those that are not familiar with this syndrome, it occurs when you take medication that has high levels of serotonin which build up in your body. This commonly happens when you increase the dosage of a drug or introduce a new medication into your drug regime.

If you are unfamiliar with what serotonin does, it is needed for your nerve cells and brain to function. If you have too much serotonin in your body, that can produce adverse effects on your body as well. In fact, sometimes serotonin syndrome can be fatal if it isn’t treated by a doctor.

But, if it is a mild case then there is the possibility that it will clear up within a few days of ceasing the intake of the medication causing it. (2)

What is Hydrocodone?

Like its cousin, Hydrocodone is also an opiate. Like Tramadol, it is used to treat various levels of pain. It is derived from the opium alkaloid codein which is found in opium poppy.

Unlike its cousin, however, it is more likely to become addictive. Hydrocodone has the potential of being habit-forming, even at the regular dosage. It also has the potential to cause permanent withdrawal in infants if taken during pregnancy.

As stated, at the beginning of this article, all medications have side effects, and this one is not an exception. One of the common side effects it shares with its cousin, however, is serotonin withdrawal. The other symptoms may be a lot more problematic. (3)

What are the Side Effects of Hydrocodone?

There are a handful of side effects that are necessary to look for. You may want to stop taking this medication if you experience any of these below symptoms.

• Breathing problems
• Discomfort during urination
• Feeling confused
• Tremors
• Severe drowsiness
• Light headedness
• Missed menstrual cycles
• Loss of sex drive
• Nausea/vomiting
• Lack of appetite
• Weakness

Tramadol and Hydrocodone have many similar properties such as being from the opioid family. However, in choosing which drug to use, it is essential that seek the advised of trained medical professionals.

References

Sansone, R. A., & Sansone, L. A. (2009, April). Tramadol: Seizures, Serotonin Syndrome, and Coadministered Antidepressants. Retrieved July 30, 2017, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714818/

Hydrocodone: Uses, Side Effects & Dosage Guide. (n.d.). Retrieved July 30, 2017, from https://www.drugs.com/hydrocodone.html

Tramadol Side Effects in Detail. (n.d.). Retrieved July 30, 2017, from https://www.drugs.com/sfx/tramadol-side-effects.html

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Gabapentin Dosage And Overdose Signs

What is Gabapentin?

Gabapentin is used primarily in the medical world. It is often prescribed to patients who have epileptic tendencies, seizures, nerve pains (neuropathic pains), and to some extent to patients who are suffering from restless legs syndrome (RLS).

If you are prescribed with the medicine, make sure to inform your doctor about your health status. Gabapentin may not be compatible with other forms of medications. Pregnant women should not take Gabapentin since it can largely affect the whole composite of the fetus.

The primary target of the medicine is the nerves and tissues responsible for the seizures and epileptic signs. Hence, it is called as an anticonvulsant.

Gabapentin can significantly affect your reactions and cognitive ability. Therefore, it is not appropriate to take a dosage of it when you are about to drive or do work which requires mental alertness.

How Should You Take Gabapentin?

You should seek the assistance of medical professionals before you take Gabapentin. Doctors often prescribed this medicine in an increasing dosage.

For example, in three consecutive days, 300 mg should be taken on the first day. Then, an additional 300 mg is taken on the second day, making a total of 600 mg.

Another dose of 300 mg on the third day sums up the total dose to 900 mg. On the first day, you have to take Gabapentin once; the second day, twice; and, the third day, thrice.

Studies have shown that the time of intake may also affect the effectiveness of Gabapentin. The Horizant brand can offer best results when taken at 5:00 in the evening.

Always take the doses with food to avoid unnecessary complications. Guidance will be provided to you by your attending physician. (1)

Signs of Gabapentin Overdose

An overdose of Gabapentin may happen if you take too much of the required dosage. If you skipped a dose, do not take an extra dosage to cover up the missed dose.

We have listed some overdose signs below which will signal you to seek immediate medical attention as soon as possible. (2)

1. Lethargy- It is a state wherein you feel weak, or as if you have no energy to do things around
2. Diarrhea- Probability of occurrence may increase if one takes the drug with an empty stomach
3. Ataxia- Some users report that Gabapentin overdose can also be characterized by partial or full loss of bodily control
4. Increase risk of suicide- In 2009, the Federal Drug Authority had issued a warning on the use of Gabapentin.

If these signs are seen, call or go to the nearest medical center the soonest possible.

Indeed, Gabapentin is a helpful tool for epileptic patients and other related diseases. However, one must be responsible for his actions. In case you are not sure about the dosage to take, the brand, and other relevant factors, it is best to avoid the drug until further instructions from your doctor.

If other allergies and other symptoms arise, other than the overdose symptoms mentioned above, seek medical attention as soon as possible. Always consult your physician if you have doubts about a particular medicine.

 

References

Backonja, M. G. (2003). Gabapentin dosing for neuropathic pain: evidence from randomized, placebo-controlled clinical trials.

Klein-Schwartz, W. S. (2003). Characterization of gabapentin overdose using a poison center case series.

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Can You Get High On Gabapentin?

Effect of Gabapentin on the Brain

Gabapentin is a drug used primarily to treat symptoms like seizures and epilepsies. It, however, has also been approved by the Food and Drug Administration of the United States. It has been promoted under the brands Horizant, and Neurontin.

The drug is sometimes used as a pain reliever for neurotic pain caused by some diseases like shingles. However, unlike other pain relievers, Gabapentin is neither an opiate nor a narcotic. Hence, the threat of its abuse or misuse has been disregarded for years.

Nevertheless, drug agencies are starting to get alarmed by reports that this once thought to be harmless drug is starting to become a nationwide problem. Data have shown that there may be a growing trend in the recreational of Gabapentin. (1)

Euphoric Effects of Gabapentin

Some Gabapentin users have reported that by taking a high dosage of the drug, one can have a similar “high” effect as marijuana. There are also some testimonies that the drug has helped them become more sociable in large groups of people.

Another potential effect of Gabapentin is a sense of relaxation, or sedation which attracts many drug abusers. When used alongside other depressants, a user can experience high levels of sedation. This is not recommended as it may result in deadly side effects such as cardiac arrest if done improperly.

Gabapentin has a low toxicity level compared to other drugs like heroin or morphine. However, there have been instances that people taking the drug for recreational purposes resulted in an overdose.

Why Is the Recreational Use of Gabapentin Becoming Popular?

Since it was approved as a pain reliever for the pain caused by shingles in 2002, the prescription and purchase of Gabapentin has increased exponentially. Many blame the lack of restrictions on the drug. However, some argue that there may be other factors affecting its popularity among recreational users. (2)

Here are some possible reasons why the drug’s recreational use have been increasing in the past years:

1. Affordability– Gabapentin is significantly cheaper compared to other abused drugs. The average cost of each pill will cost a person merely 60 cents. It can also be bought in varying dosages such as 100 mg, 300 mg, and 400 mg.
2. Drug Withdrawal– Some doctors prescribe Gabapentin to persons undergoing drug rehabilitation to combat some of the withdrawal symptoms that they are experiencing. Sadly, some people end up shifting their addiction to Gabapentin instead. (2)
3. Accessibility– Being non-narcotic Gabapentin is not classified as a controlled substance by the FDA. Thus, anyone can obtain it with a simple prescription from their doctor.
4. Lesser Side Effects– While Gabapentin may have lesser side effects compared to other drugs, it worth noting that there still have been instances where patients died due to overdose.

Gabapentin is seen as a miracle drug by some people experiencing seizures and epilepsies. Some may have found a recreational use for it; however, it is still highly unadvisable to abuse it. Always consult your doctor before taking this drug, and remember only to take as much as your doctor has prescribed you.

References

Schifano, F. (2014). Misuse and abuse of pregabalin and gabapentin: cause for concern?

Smith, B. H. (2012). Substance misuse of gabapentin. British Journal of General Practice.

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What are the Side Effects of Gabapentin?

Side Effects of Gabapentin

Whenever we take a new type of drug, it is important for us to know every single detail about it. This is to prevent any unwanted side effects that may occur in the future. Some drugs are prohibited to some types of persons, most especially those who have allergies towards them.

Gabapentin, most famous for the brands Horizant or Neurontin, is a prescription anticonvulsant. It is used to treat, prevent, or control seizures alongside other drugs. Some doctors also prescribe it for those that suffer nerve pain brought about by shingles in adults.

The drug was approved by the United States’ Federal Drug Authority as an anti-seizure medication for adults way back in December 1993. Its use on children, however, was only approved in 2000. Their pain reliever property was only recognized in 2004. (1)

Just like any other drug, Gabapentin can result in various side effects when misused. Here is a look at the most common side effect Gabapentin users have reported.

Most Common Side Effects of Gabapentin

Here are some of the most common and less dangerous side effect of Gabapentin:

1. Sleepiness- doctors require adults that use Gabapentin to avoid doing tasks which require mental alertness and consciousness while under the influence of the drug. This side effect occurs most especially for those who are taking the drug for the first time. Some patients report that the drowsiness caused by Gabapentin is almost impossible to overcome. Hence, it is recommended to avoid driving at all costs. (2) 
2. Headache- patients may experience some throbbing pain as the drug reaches the brain. This is caused by sudden changes in the chemistry of the user’s brain.
3. Irritable Bowel Movement- some patients report that taking the drug on an empty stomach may result to stomach pain, indigestion, constipation, or diarrhea.
4. Ataxia- more commonly known as clumsiness. It results in a lack of coordination between our voluntary muscles. It is best to ask Gabapentin users to take a seat during the first hours of taking the drug.
5. Sexual Dysfunction- although temporary, research have shown that some users can have problems with their sex lives. Some of the challenges they may encounter are the loss of libido, inability to reach orgasm, and erectile dysfunction. (3)
6. Tremors- uncontrollable rhythmic muscle contractions that may occur in one or more body parts.

Serious Side Effects of Gabapentin

These side effects can happen if a person gravely misuses the drug or outside of how doctors have prescribed it to them:

1. Increase risk of suicide- In 2009, the Federal Drug Authority had issued a warning on the use of Gabapentin. This was due to reports of patients having increased suicidal thoughts while under the drug, and indeed this claim was proven by a 2010 research on the drug. (4)
2. Overdose- using the drug beyond the prescribed amount increases the risk of overdose. It is worth noting that there have been reports of deaths due to Gabapentin overdose. Taking the drug alcohol also increases the risk of overdose.
3. Allergic Reactions- Before using Gabapentin ask your doctor to advise you on how to assure that you are not allergic to the drug.
4. Addiction- reports have shown that the drug has a considerable abuse potential due to the high some users get while under Gabapentin

Gabapentin is a useful drug for people afflicted with seizures. However, one must always take precautions to avoid experiencing the adverse effects of the drug. Remember to always consult your doctor before taking any new medications.

References

Pitkänen, Asla; Schwartzkroin, Philip A.; Moshé, Solomon L. (2005). Models of Seizures and Epilepsy. Burlington: Elsevier. p. 539. ISBN 9780080457024

Patorno E, Bohn RL, Wahl PM, et al. (April 2010). “Anticonvulsant medications and the risk of suicide, attempted suicide, or violent death”. JAMA. 303

Jeffrey K Aronson (4 March 2014). Side Effects of Drugs Annual: A worldwide yearly survey of new data in adverse drug reactions. Newnes. p. 137. ISBN 978-0-444-62636-3.

Smith, B. H. (2012). Substance misuse of gabapentin. The British Journal of General Practice , 601.

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Should You Mix Tramadol With Alcohol?

Tramadol and Alcohol Consumption

Mixing alcohol with different types of drugs can result in various consequences. The same way as any food can affect the way a drug will affect your body. Some mixtures can improve the effectiveness of a drug, while others can lessen it or worse amplify its dangerous side effects.

Tramadol is a very powerful depressant, meaning it works by dulling the receptors inside the brain. On the other hand, alcohol can sometimes work as either a depressant or a stimulant. This contradiction can cause an imbalance inside a brain which may result in dangerous circumstances.

How Does Alcohol Affect the Brain?

After consumption, alcohol passes through the bloodstream towards the liver. Alcohol molecules that the liver failed to breakdown would then be redistributed in various parts of the body. The body part whose effect is most noticeable is the brain. (1)

Alcohol is often mistaken as a stimulant rather than the depressant. This is why people use it to suppress their mental limitations during social gatherings. However, as can be seen at the end of every party, after a person has drank a considerable amount of alcohol it then turns to a powerful depressant.

Medically speaking, alcohol is tagged as a depressant because like sedatives and tranquilizers. It works by slowing down the activities of our central nervous system. At the same time, alcohol stimulates the brain into release dopamine, usually described as the “feel good” hormones. (2)

How Does Tramadol Affect the Brain?

The Tramadol is primarily used to relieve moderate to severe pains. It does this by binding with the brains opioid receptors in order to limit the stimuli entering the brain. In small doses, it reduces the pain that is felt by the user, but with higher doses, it can produce a euphoric effect which makes it attractive to some drug abusers.

Since the drug is considered as milder than other narcotics such as heroin and morphine, many doctors consider it as a safer alternative. However, its adverse side effects can be just as worse is abused.

It also produces a secondary opioid receptor known as O-desmethyltramadol. This receptor actually produces a stronger depressant effect than Tramadol itself. That is why some users report getting high while using the drug even after following their doctor’s prescriptions.

Side Effects of Mixing Alcohol and Tramadol

Taking alcohol and Tramadol together will produce twice the depressing effects of each when taken separately. This mix will result in multiple adverse effects which can be seriously life threatening.

1. Seizures- It is characterized by uncontrollable tremors and shakings throughout the body. It is incredibly dangerous for unsupervised individuals dues to the fact that it can cause breathing problems.
2. Extreme Anxiety
3. Nausea and Stomach Discomfort- the outcome of the tramadol’s reaction with the alcohol while it is still in the stomach
4. Respiratory Depression- The same way the heart loses function; many users end up with asphyxiation after their lungs became unable to work properly.
5. Bradycardia or Slowed Heart Beat
6. Cardiac Arrest- Overly decreased brain function can result to important organs shutting down. Cardiac arrest is the sudden stop of the heart from beating.
7. Loss of Consciousness

References

Alcohol Use and Older Adults. (n.d.). Retrieved July 26, 2017, from NIH Senior Health: https://nihseniorhealth.gov/alcoholuse/howalcoholaffectsthebody/01.html

NewBridge: Is Alcohol a Stimulant or a Depressant? (2016, February 15). Retrieved July 26, 2016, from New Bridge Recovery: http://www.newbridgerecovery.com/newbridge-is-alcohol-a-stimulant-or-a-depressant/

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Signs And Symptoms Of Tramadol Abuse

Tramadol Abuse

Taking Tramadol as prescribed by the doctor can be a safe and effective medication against moderate to severe pain. On the other hand, abusing it can result to destructive or even deadly outcomes. The drug was intended as a powerful weapon against pain, sadly some people are now starting to abuse the drug for its unintended use.

There are many ways to know if someone you know or close to you are abusing Tramadol. Being equipped with this knowledge can help you save someone you love from the dangerous side effects of Tramadol addiction. And if you yourself is taking Tramadol, this can help you when it’s time to stop and drop the drug.

Tramadol Abuse Side effects

Before we tackle the symptoms of Tramadol abuse, it is wise for us to first know some of the dangers of abusing Tramadol. Listed below are some of the serious side effects of Tramadol abuse.

1. Seizures– the psychoactive property of Tramadol greatly affects the way the body sends signals to the brain. Overdosage of Tramadol can result to the brain overloading sending a person into violent and dangerous seizures.
2. Kidney Failure– The kidney is the main organ responsible for filtering toxins in our blood streams. An abundant supply of Tramadol will force your kidneys to work in overdrive which can inevitably result to failure.
3. Addiction– contrary to what people often think, drug abuse and addiction are two different things. Abuse is when one uses a substance beyond what should be, while addiction is dependence on the substance to function properly. (1)
4. Death– flooding the body with any psychoactive drug can result to the brain failing to send signals to important parts of the body such as the lungs or heart.

How To Know If Someone Is Abusing Tramadol

Some quick ways to know is someone you know has been abusing their Tramadol supply:

1. Always Low on Supply– you may notice that their supply is always running low even when they just recently visited their doctor to get a new prescription for the drug.
2. Complain about the Drugs Ineffectivity– when a person abuses Tramadol, their body eventually becomes numb to the effects of the drugs. Hence, the patient would need to drink a more and more of the drug for it to work.
3. Using More Than What is Prescribed– data has shown that the safest amount of Tramadol that an adult can take on a daily basis is around 400mg. If a patient starts taking more than this without a doctor’s permission, then it is very likely that they are abusing the drug.

Tramadol is a safer alternative compared to other opioids like morphine and heroin, however, the dangers posed by abusing it is no less than the latter. If you know someone who might be abusing the drug or someone showing some of the signs above, it would be best to refer them to a doctor to get them checked.

References

Difference Between Abuse and Addiction. (n.d.). Retrieved July 26, 2017, from Dual Diagnosis: http://www.dualdiagnosis.org/drug-addiction/abuse-and-addiction/

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Tramadol Addiction and Withdrawal Symptoms

This article shall tackle symptoms that could help determine whether a person has become addicted to Tramadol, and the withdrawal symptoms they may experience as they begin the detoxification.

Why is Tramadol so Addictive?

Narcotic drugs like Tramadol work directly alongside the human brain receptors. This action results to sensations that are both fulfilling and relaxing to users. This is why many users find using the drug the easiest way for them to get through their day.

However, as patients rely more and more on the drug to help them ease their pain, their bodies slowly become numb to the effects of the drug. A chain of events leads to the person drinking more until they reach a point where they find it almost impossible to live normally without the drug.

As their dependence worsens, the side effects of the drug start to take a toll on their overall health. If they are left to continue their dangerous cycle, many of these patients end up overdosing themselves.

Symptoms of Tramadol Addiction

Drug addiction can manifest in different forms, the most common ones are as listed below: (1)

1. Heavy Use– one of the most noticeable symptoms of Tramadol addiction is when a patient starts using above the prescribed amount their doctor has given them. The maximum amount doctors are allowed to prescribe the drug is placed at 400mg per day. If your body is forcing you to drink more than that, then it is safe to assume that you may have an addiction.
2. Finding ways to get prescribed more– addicted patients may try to find excuses, such as they lost their supply or that the prescribed amount is not working anymore, to get their doctors to give them a fresh supply of Tramadol.
3. Constantly looking for other sources– some patients may try to visit various doctors for the same problem or attempt to forge prescription form for them to be able to buy more of the drug in pharmacies.
4. Over Dependence– over dependence can be seen when the patient needs to drink the drug in order to do simple everyday things. Without the drug, the patient may feel like they have no energy to do things that were once routinary to them.

Symptoms of Tramadol Withdrawal

Stopping Tramadol addiction is a very beneficial choice, however, it is not as easy as it looks due to the withdrawal symptoms that come along with it.

1. Nausea– the uneasy feeling a person feels when they are about to vomit. This is the way our brain tells us that there is something wrong with our stomach or digestive system. (2)
2. Muscle cramps– painful uncontrollable muscle contractions that can last between a few seconds to a minute. (3)
3. Irritable bowel syndrome– characterized by painful sensations usually located in the large intestines such as diarrhea, constipation, stomach cramps, and bloating. (4)
4. Anxiety- an uneasy feeling that something wrong or terrible might happen, can be mild or severe (5)
5. Depression- various permanent or temporary emotions characterized by the feeling of hopelessness or the lack of motivation to do simple everyday things. (6)
6. Insomnia- the inability to sleep for a few days or to sleep consistently during the night.

Recreational Use of Tramadol

Reports have shown that drug users have started using Tramadol to fulfill their thirst for a hit of euphoria. With the drug becoming more and more accessible to the masses, some people have started snorting the crushed form of the drug. Using Tramadol for such purposes will result in more severe side effects and later on withdrawal symptoms. (7)

References

Mayo Foundation for Medical Education and Research. (n.d.). Irritable bowel syndrome. Retrieved July 26, 2017, from Mayo Clinic: http://www.mayoclinic.org/diseases-conditions/irritable-bowel-syndrome/basics/definition/con-20024578

MediLexicon International Ltd. (n.d.). Signs And Symptoms Of Addiction . Retrieved July 26, 2017, from Medical News Today: http://www.medicalnewstoday.com/info/addiction/signs-of-addiction.php

Muscle Cramps – Topic Overview. (n.d.). Retrieved July 26, 2017, from Web MD: http://www.webmd.com/sleep-disorders/tc/nighttime-leg-cramps-topic-overview#1

National Health Services. (2016, May 10). Clinical depression . Retrieved July 26, 2017, from National Heath Services: http://www.nhs.uk/conditions/depression/Pages/Introduction.aspx

National Health Services UK. (2016, January 2). Generalised anxiety disorder in adults . Retrieved July 26, 2017, from National Health Services UK: http://www.nhs.uk/conditions/Anxiety/Pages/Introduction.aspx

Nausea and Vomiting. (n.d.). Retrieved July 26, 2017, from Web MD: http://www.webmd.com/digestive-disorders/digestive-diseases-nausea-vomiting#1

Snorting Tramadol. (n.d.). Retrieved July 26, 2017, from Rehabs.com: http://luxury.rehabs.com/tramadol-addiction/snorting/

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How Long Does Tramadol Stay In Your System?

Estimated Time the Body Excretes Tramadol

Tramadol is a drug exclusively used to treat varying degrees of pain. It is often used for lingering pains. Psychoactive drugs like Tramadol only maintain their effectiveness as long as their components still exist in the user’s body. Being able to know the length of time the drug stays in the body will help us time and measure the proper amount of drug that we should take.

Another reason it is important to know how long Tramadol stays in the body is that most blood tests can detect the presence of Tramadol molecules in the user’s blood stream. Having remnants of the drug on our body can cause blood examination to yield faulty results.

Length of Time Tramadol Stays in the Body                

For us to fully comprehend how long the drug can stay in our body, we need to first discuss the idea of elimination half-life. The University of Lausanne of Switzerland defines elimination half-life as the “Time it takes for the plasma concentration or the amount of drug in the body to be reduced by 50%.” (1)

The United States institute of Health places Tramadol’s elimination half-life at around six to seven hours. This means that the amount and effectiveness of the drug to reduce pain drops to half in around six to seven minutes. (2)

By further applying the concept of elimination half-life, it can be determined that detectable traces of Tramadol can linger inside the body for as long as a day and a half. The longest lasting component of Tramadol is its primary metabolite “O-desmethyltramadol”.

This component can stay inside the body for another 7.4 hours after other components have been metabolized by the body. Hence, Tramadol can only be fully eliminated in our body 1.7 days from ingestion. These data are all based on controlled environments. The true time at which the drug can stay inside the body can be affected by different variables.

Variables that Affect How Long Tramadol Stays in the Body

Personal Factors

The length drugs such as Tramadol stay in our body can be affected by our overall health and physique. Older people whose metabolism has significantly decreased can have higher Tramadol elimination half-life than their younger counterparts.

Our body mass has a two-fold effect on the drug’s persistence. People with higher body mass can eliminate the drug faster from their body, however, they larger people who have had Tramadol addiction have a longer detoxification period since the drug molecules bind to fat stores making accumulation easier.

Many more individual factors can significantly affect the timing of the drug such as genetics, nutrient intake, the status of the kidney and liver, urinary ph, and personal metabolic rates. (3)

Dosage

Common sense dictates that the quantity of drug a person takes will significantly affect the length of time that drug would stay in the person’s body. A study has shown that people who have overdosed with Tramadol have drug elimination half-life increased to 9.24 hours.

Presence of Other Drugs

People who consume other drugs at the same time as Tramadol can either have a longer or a shorter half-life. This is because some substances can alter the metabolism of the metabolite “O-desmethyltramadol”. Caution must be made when drinking Tramadol alongside other drugs. Doing so could result to unforeseen and dangerous side effects.

Kind of Tramadol Taken

There are two type of Tramadol available in the market, IRs or immediate release Tramadols are excreted faster by the body compared to ERs or Extended release Tramadols.

Detectability of Tramadol with Drug Tests

Data show that the drug is not completely detectable with standard drug tests, however, more complicated and advanced screening methods can definitely detect its presence in the blood stream. Tests to detect Tramadol can either be hair tests, urine tests, saliva tests – or in some cases, blood tests. (4)

The knowledge of the length of time Tramadol stays in our body is very important in situations that we need to have our body chemistry tested. Various factors can determine how long the drug can truly stay inside someone’s body, thus, it is always best to consult your doctor to know more about the topic.

References

HALF-LIFE. (n.d.). Retrieved July 25, 2017, from University of Lausanne: http://sepia.unil.ch/pharmacology/?id=60

How Long Does Tramadol Stay In Your System? (n.d.). Retrieved July 25, 2017, from Mental Health Daily: http://mentalhealthdaily.com/2015/11/06/how-long-does-tramadol-stay-in-your-system/

TRAMADOL HYDROCHLORIDE. (n.d.). Retrieved July 25, 2017, from National Institute of Health: https://dailymed.nlm.nih.gov/dailymed/archives/fdaDrugInfo.cfm?archiveid=20655

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Is Tramadol An Opiate Or Narcotic?

Where Does Tramadol Stand?

Many people have trouble determining whether Tramadol is an opiate or a narcotic. Before we answer this questions we first need to know a couple of important things, such as the differences between opiates and narcotics, how drugs are categorized, and the importance of knowing what category a drug belongs to.

Opiates vs. Narcotics

Narcotics

The term narcotics refer to a group of drugs that have psychoactive properties and sleep inducing properties. The, term however, has been more commonly used in the streets as a description for illegal and dangerous drugs. However, the medical community maintained the generic definition of the term without the negative connotations. Two of the most common drugs under narcotics are morphine and heroin. (1)

Opiates

Narcotics is the main branch of several other types of drugs. One of its sub categories is known as opiates. Opiates are naturally occurring alkaloid substances that are harvested from the opium poppy plant Papaver somniferum. These substances work by binding their molecules to our brain’s opioid receptors. (2)

People often use opiates for recreation due to its ability to block pain stimuli from entering our brains. This gives the user a sense of high and euphoria. It has become one of the most popular kinds of illegal drugs due to its availability. (3)

Opioids were originally described as the synthetic version of opiates. However, as time went by, the term opioid was adopted to refer to both synthetic and natural opiates. Hence, opiates are now considered as a subcategory of the term opioids.

How Drugs Are Categorized

There are hundreds of psychoactive drugs available in the market. The most famous of which are morphine, heroin, opiates, caffeine and more. Drugs are often categorized based on the manner in which they affect the brain of the user

The four most common classifications of controlled drugs are: (4)

1. Narcotics- psychoactive drugs with sleep inducing properties which are used as pain reliever
2. Depressants- suppresses the brain’s activity resulting to a calming or sedating effect
3. Stimulants- accelerates the brain’s activity to induce alertness or focus
4. Hallucinogens- alters the user’s perception of reality, time and space.

Importance of Drug Categorization

It is important to know which category a certain drug belongs to because each category describes how a drug can affect a person. It can determine whether it would be safe to prescribe it and the amount at which it should be prescribed to each type of person.

For example, depressants cannot be prescribed to people with depression, while narcotics cannot be consumed by a person whose job description requires them to stay awake (i.e. operators of public transports, or heavy machinery).

Conclusion

Tramadol works by affecting the brain’s molecules to reduce the pain felt by a person, thus it can be categorized as a narcotic. However, Tramadol can further be categorized under opioid because of its pain relieving properties. Note that not all opioid are opiates since opiates require that a drug came from natural sources to be categorized as such. Being a synthetic drug, Tramadol is not an opiate.

References

“Opiate – Definitions from Dictionary.com”. dictionary.reference.com. Retrieved 2017-07-25.

Julien, Robert M. A Primer of Drug Action. 11th edition. Claire D. Advokat, Joseph E. Comaty, eds. New York: Worth Publishers: 2008. page 537.

NIDA. (2016, August 1). Misuse of Prescription Drugs. Retrieved from https://www.drugabuse.gov/publications/research-reports/misuse-prescription-drugs on 2017, July 25

Balhara, Y. P. (n.d.). Drug Classifications. Retrieved July 25, 2017, from Rehabs: http://luxury.rehabs.com/drug-abuse/classifications/

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What Are The Side Effects Of Tramadol?

Side Effects of Tramadol

Tramadol is a psychoactive narcotic that is used mainly to treat moderate to moderately severe pain. It acts by blocking the pain receptors of the brains. It is famously sold under the brand name Ultram which is a strictly as prescribed only drug.

The side effects of Tramadol may differ from person to person. This is why Tramadol may only be taken if the doctor has made sure that it will not adversely affect a person’s health or well-being.  The severity of those side effects also depends on the amount at which a person consumes the drug.

This article will discuss the most common side effects experienced by patients when taking in Tramadol. It will also elaborate how this side effect may prohibit a certain type of person form taking the drug.

Common Side Effects of Tramadol (1)

1. The depressant properties of Tramadol can often result to headaches, drowsiness, dizziness, or fatigue.
2. It is common for people to experience constipation, diarrhea, nausea, vomiting, or stomach pain when taking the drug with an empty stomach.
3. Anxiety often occurs to people that decide to stop taking the drug after a long-term exposure to Tramadol.
4. Users often report sweating, itching, and flushing- the reddening of the skin- in various parts of the body.

Severe Side Effects of Tramadol

1. Allergic Reactions- people allergic to Tramadol can experience difficulty in breathing, hives, swelling of various parts of the body such as the face, tongue, lips or throat. Before taking the drug, a doctor must first determine whether a person is allergic to the drug.

2. Seizures- some patients have reported experiencing seizures after taking in Tramadol, this symptom is also very common among people to abuse the drug and take it nasally.

3. Addiction-Like most psychoactive drugs, prolonged use and abuse of Tramadol can result to addiction. Some patients report that the euphoric high gets them hooked on the drug, and then physical dependence takes over thus making it hard to get over the addiction.

4. Kidney Failure- Taking excessive amount of Tramadol can put a strain on a person kidney which could eventually result to kidney failure.

5. Death- Drug overdose is a very serious danger posed by abusing Tramadol. Being a prescription drug, many people downplay the dangers of using Tramadol. (2)

People Who May Be Disallowed to Take Tramadol

1. People with severe asthma, or other breathing problems.
2. Those with blockages in their intestines or stomachs.
3. People that recently drank alcohol, or taken in other sedatives, narcotics, or sedatives.
4. Children aged 12 and below
5. Patients afflicted with seizure disorders as they can be triggered by Tramadol
6. Breastfeeding women
7. People that plan to have a long drive after taking the drug (1)(3)

For some people, Tramadol may be their last hope to get relief from the pain that they suffer. However, extra precautions must be made to avoid the various side effects that can happen to a Tramadol user. Remember to always consult your doctor before taking the drug Tramadol yourself.

References

Tramadol. (n.d.). Retrieved July 25, 2017, from Drugs.com: https://www.drugs.com/tramadol.html

Tamplin, H. (2016). Prescription painkiller that ‘claims more lives than heroin’. United Kingdom: Metro News.

Tramadol HCL. (n.d.). Retrieved July 25, 2017, from WebMD: http://www.webmd.com/drugs/2/drug-4398-5239/tramadol-oral/tramadol-oral/details#interactions

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Can Tramadol Make You High?

The Psychological Effects of Tramadol

Our brain is considered as the command center of our whole body. Every movement we make and every thought that comes to our mind comes from this humble pink mass. Thus, it should be no surprise that anything we experience or consume can have either a positive or a negative effect on the way we think or move.

The same way a chocolate bar can make your brain function better, a sip of coffee jumpstart your senses or the smell of chamomile tea can make you sleepy, drugs can affect your overall behavior.

What is Tramadol?

Tramadol, most famously known as Ultram, is a powerful opioid drug most commonly used to treat moderate to severe pain. It has a chemical structure of C16H25NO2 and has been clinically tested to reduce pain within an hour since oral consumption. (1)

Pain relievers, such as morphine, oxycodone, tramadol, and much more, work by blocking the pain receptors that are connected to the brain. Drugs like this are considered depressants meaning they decrease the number of stimuli that reach the brain thus increasing the feeling of relaxation. (2)

Emergence of Tramadol Abuse and Overdose

Some drug abusers have started snorting a powdered form of tramadol in order to get a high from it. However, its effects are still far less than other opioid drugs; thus, making it a little bit safer than others. That is why the WHO has classified it as a low abuse potential drug.

What makes the drug dangerous is its availability and how it is getting easier and easier to acquire the drug. According to US government statistics, 43 million tramadol prescriptions were handed out by doctors in the US alone.

What’s scarier is that the World Health Organization has issued an alarm on the rate at which tramadol is getting more available for purchase through the internet without the need for any prescriptions. (3)

The depressant effect of tramadol is relatively harmless in a short-run; however, continued use and misuse can lead to addiction. Prolonged use may result in the user needing the drug to feel normal or to avoid withdrawal symptoms.

Since tramadol is processed by the body through the liver, consuming beyond the prescribed amount of it could result in kidney failure. It has also been reported to cause seizures among those that abuse it. (4)

Conclusion

High doses of tramadol can indeed induce a euphoric high. However, it is not as severe as other opioid drugs such as heroin, or morphine. Nevertheless, there is no definite dosage at which point a person would get high using tramadol.

As with most drugs, the effects vary from person to person. A tablet of tramadol could induce relaxation on one person whilst do nothing on another.

With all these said, using tramadol can indeed make some people high. However, the risk involved in doing so far exceeds the euphoria that a person can get from it. It would be safest to use tramadol for purposes that it was really made for.  Finally, it would be best to consult a doctor to know the recommended amount at which you should take this drug.

References

Katz WA (1996). “Pharmacology and clinical experience with tramadol in osteoarthritis”. Drugs. 52 Suppl 3: 39–47. PMID 8911798. doi:10.2165/00003495-199600523-00007

Expert Committee on Drug Dependence. (2014). Tramadol Update Review Report. Geneva: World Health Organization.

Hokemeyer, P. (2014, July 2). The Effects of Painkillers on the Brain and Body. Retrieved July 24, 2017, from Maryland Addiction Recovery Center: http://www.marylandaddictionrecovery.com

Savage, R. (2007, October). Serious Reactions with Tramadol: Seizures and Serotonin Syndrome. Retrieved July 24, 2017, from New Zealand Medicines and Medical Devices Safety Authority: http://www.medsafe.govt.nz

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What Is Tramadol Used For?

Tramadol HCL is a medication taken to relieve pain. The active ingredient is tramadol, a centrally acting analgesic. The medication may relieve moderate to severe pain. It provides relief by working in the brain to change the body’s perception and reaction to pain.

Uses of Tramadol

Tramadol contains codeine, which binds to mu opiate receptors to inhibit the reuptake of norepinephrine and serotonin. It works quickly, with the effects beginning within an hour after taking the dose and having the most effect in about two hours. Tramadol HCL is metabolized in the liver.

Tramadol is equally effective as meperidine, codeine, or morphine for treating moderate postoperative pain, labor pain, acute dental pain, and other types of chronic pain. Tramadol is less effective than other medications for severe acute pain, ureteral calculi, and certain severe or refractory pain from cancer. (1)

Things to Remember When Taking Tramadol

Do not take Tramadol HCL if you are:

• Allergic to Tramadol HCL
• Pregnant or planning to be (2)
• Have recently had alcohol, sleeping tablets, or other strong pain killers.

More information to know before taking Tramadol HCL include:

• Let your doctor know of other medications you are taking as there may be possible drug interactions.
• Do not consume alcohol while using this medication.
• Pain medications work best if taken as the first signs of pain occur, rather than waiting for the pain to worsen.
• Taking painkillers for headaches too often or long can make the pain worse.

When and How Much To Take

• Adults and children above 12 years of age (children under 12 should not use this medication):
• Acute pain: 1-2 capsules 3-4 times daily
• Chronic pain: 1-2 capsules at first and then 1-2 capsules every 4-6 hours depending on pain severity
• Elderly: 1-2 capsules every 9 hours
• Patients experiencing liver or kidney problems: 1-2 capsules every 12 hours (3)

Some Common Effects of The Drug

Tell your doctor if you experience side effects including but not limited to the following. Common side effects include dizziness, feeling sick, sweating, drowsiness, body aches, and constipation. Uncommon side effects include itchiness, irregular heartbeat, dizziness on standing, and retching. (4)

Rare side effects may include a sense of euphoria, dysphoria, confusion, hallucinations, delirium, sleeping problems, anxiety, and slow heart beat.

Warnings when Taking Tramadol

Ensure you are not drowsy or dizzy and that your vision is clear before attempting to operate machinery or drive while on this medication.

You may become dependent on tablets and experience withdrawal if you stop taking them suddenly. Withdrawal symptoms include restlessness, watery eyes, nausea, and muscle aches.

Tell your doctor if pain remains or worsens or if the medication stops working as well.

Conclusion

Tramadol HCL is a viable pain killer for a wide range of situations. Tramadol HCL may be more or less effective than other medications depending on the location and severity of pain. It is effective in treating the pain so long as warnings and precautions are in mind. Keep in mind to take the correct dosage and be attentive of side effects.

References

Lewis, K., & Han, N. (1997). Tramadol: a new centrally acting analgesic. American Journal of Health System Pharmacy .

Tramadol. (n.d.). Retrieved July 25, 2017, from Drugs.com: https://www.drugs.com/tramadol.html

Tramadol hydrochloride 50mg capsules. (n.d.). Retrieved July 25, 2017, from Drugs.com: https://www.drugs.com/uk/tramadol-hydrochloride-capsules-50mg-1354.html

 

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